Moore: A Non-Opioid Remedy for Persistent Ache| Staff Compensation Information

By James Moore

Tuesday, June 8, 2021 | 0

Researchers at the Medical College of Wisconsin have discovered a non-opioid treatment for chronic pain that could revolutionize the management of severe pain.

James Moore

A recent article in the Medical Xpress newsletter looked at what may be a new way to treat chronic pain, including workers’ compensation insurance.

TRPC5 Keys to Non-Opioid Treatment

According to the article, blocking the canonical activity of transient receptor potential 5 (TRPC5) reversed touch pain in mouse models of sickle cell anemia, migraines, chemotherapy-related pain, and surgical pain.

If you want to learn more, the MCW staff have put together a lovely research video. The video is a little heavy on medical terms, but the bottom line is a new method of pain relief is on the horizon.

While research is still in its infancy, it appears to be an important step in pain control.

Two TRPC5 inhibitors are currently in clinical trials for the treatment of kidney disease and depression. Until the phase 1 safety tests are successfully completed, these drugs could potentially be rapidly used for use in chronic pain sufferers.

This means that TRPC5 could be a new, non-opioid target for pain relief in the chronic inflammatory pain conditions that affect so many patients around the world. In addition, realizing that TRPC5 had no effect on pain-free touch means people can pick up their coffee mug, walk, get dressed, and pet their grandchild without losing tactile awareness.

It will likely be years before any type of new drug hits the market unless the drugs are followed up quickly. The research group works with mice. Humans and mice have very similar pain receptors.

I am sure that there are many studies on non-opioid treatment. This appears to be the most promising for pain relief without the all-too-known complications of opioid use.

This blog post is provided by James Moore, AIC, MBA, ChFC, ARM and republished with permission from J&L Risk Management Consultants. Visit the full website at www.cutcompcosts.com.